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Home >> Antibodies >> CD10 Antibody / Neutral endopeptidase 24.11 / Neprilysin

CD10 Antibody / Neutral endopeptidase 24.11 / Neprilysin [clone MME/8658R] (V5014)

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  Catalog No Formulation Size Price (USD)  
Image V5014-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V5014-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V5014SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recrabbitmono
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SDS-PAGE analysis of purified, BSA-free CD10 antibody (clone MME/8658R) as confirmation of integrity and purity.
SDS-PAGE analysis of purified, BSA-free CD10 antibody (clone MME/8658R) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name MME/8658R
Purity Protein A/G affinity
UniProt P08473
Localization Cell surface, Cytoplasm
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Limitations This CD10 antibody is available for research use only.
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Description

Recognizes a 100kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

Application Notes

Optimal dilution of the CD10 antibody should be determined by the researcher.

Immunogen

A recombinant human CD10 protein fragment (within amino acids 1-500) was used as the immunogen for the CD10 antibody.

Storage

Aliquot the CD10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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